INDICATIONS AND USAGE Oxycodone HCl tablets are an opioid agonist indicated for your management of pain serious ample to demand an opioid analgesic and for which choice therapies are insufficient. (1)
Coadministration with other CNS depressants: Initiate extended-acting oxycodone with just one-3rd to 1-50 percent the recommended commencing dose; check for signs of respiratory despair, sedation, and hypotension
Dose adjustment necessary when initiating prolonged launch therapy in sufferers getting other CNS depressants
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Respiratory despair may be the chief possibility for elderly sufferers treated with opioids, and has occurred immediately after substantial Original doses were administered to patients who were not opioid-tolerant or when opioids ended up co-administered with other brokers that depress respiration.
In patients who might be at risk of intracranial results of CO2 retention (e.g., All those with evidence of amplified intracranial stress or brain tumors), therapy may possibly lessen respiratory generate, and resultant CO2 retention can even more boost intracranial stress; keep an eye on these patients for signs of sedation and respiratory depression, significantly when initiating therapy; opioids may obscure clinical program in a affected person having a head injury; steer clear of the use in individuals with impaired consciousness or coma
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Generally, oxycodone tablets should not be Slash in half. Nevertheless, Should your physician directs you to just take fifty percent-tablets in the oxycodone speedy-release tablets, then it’s Safe and sound for you to Minimize them in 50 percent. If so, you must normally utilize a pill splitter to correctly Lower your tablet in 50 percent.
Accidental ingestion of even one dose of oxycodone HCl, especially by little ones, may end up in respiratory melancholy and Demise as a result of more info an overdose of oxycodone.